Phospholipase a2 gene

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August undefined, 2024

WebENCODES a protein that exhibits calcium-independent phospholipase A2 activity (ortholog); lysophospholipase activity (ortholog); O-acyltransferase activity (ortholog); INVOLVED IN …

Identification and expression of phospholipase A2 genes related …

WebCytogenetic location: 4q25 Genomic coordinates (GRCh38): 4:109,709,989-109,730,070 (from NCBI) TEXT Description Secreted phospholipase A2 (sPLA2) enzymes liberate arachidonic acid from phospholipids for production of eicosanoids and exert a variety of physiologic and pathologic effects. WebPreferentially hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity) (PubMed:7794891, ... The disease is caused by variants affecting the gene represented in this entry; Description. An autosomal recessive disorder characterized by recurrent gastrointestinal mucosal ulcers ... crypto risk reward ratio

Human Secretary Phospholipase A2 Mutations and Their Clinical …

WebPLA2 provides precursors for generation of eicosanoids, such as prostaglandins (PGs) and leukotrienes (LTs), when the cleaved fatty acid is arachidonic acid, platelet-activating factor (PAF) when the sn-1 position of the phosphatidylcholine contains an alkyl ether linkage and some bioactive lysophospholipids, such as lysophosphatidic acid (lysoPA). WebPLA2G7 phospholipase A2 group VII [ (human)] Gene ID: 7941, updated on 5-Aug-2024 Summary The protein encoded by this gene is a secreted enzyme that catalyzes the degradation of platelet-activating factor to biologically inactive products. Defects in this gene are a cause of platelet-activating factor acetylhydrolase deficiency. WebDec 1, 2024 · Phospholipase A2 (PLA2), a phospholipid hydrolase, has recently attracted attention owing to its broad functionality. Immunological evidence has revealed increased … crypto risk training

5320 - Gene ResultPLA2G2A phospholipase A2 group IIA

WebThe Val279Phe variant of the lipoprotein-associated phospholipase A2 gene is associated with catalytic activities and cardiovascular disease in Korean men. J Clin Endocrinol … WebMar 28, 2024 · In a Serbian brother and sister with GURDP, Brooke et al. (2014) identified a homozygous 4-bp deletion in the PLA2G4A gene ( 600522.0004 ). The mutation, which … crypto rivers.comWebexpression cassette with the phospholipase A2 encoding gene from the S. violaceoruber NBRC 15146 . Phosphatidylinositol-specific phospholipase C expressed in P. fluorescens (2024) Page 3 of 6 donor, a suitable promoter and terminator encoding phospholipase D from S. cinnamoneum and a ... crypto rl

"WebPLA2 provides precursors for generation of eicosanoids, such as prostaglandins (PGs) and leukotrienes (LTs), when the cleaved fatty acid is arachidonic acid, platelet-activating … " - Phospholipase a2 gene

Phospholipase a2 gene

WebSpecifically, the A2 phospholipase produced from the PLA2G6 gene, sometimes called PLA2 group VI, helps to regulate the levels of a compound called phosphatidylcholine, which is … WebGene provides a unified query environment for genes defined by sequence and/or in NCBI's Map Viewer. LOC119581056 cytosolic phospholipase A2-like [ (black tiger shrimp)] Gene ID: 119581056, updated on 4-Feb-2024. Summary Other designations. LOW QUALITY PROTEIN: cytosolic phospholipase A2-like ...

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WebApr 3, 2024 · Phospholipase A2 Group IIa may be a modifier gene for fundic gland polyposis in patients with familial adenomatous polyposis PLA2G2A haplotypic variation strongly … WebPhospholipase A2. Phospholipase A2 (PLA2) is one of a family of phospholipases, enzymes that hydrolyse phospholipids. From: Clinical Biochemistry: Metabolic and Clinical Aspects …

WebBackground Ureases are multifunctional enzymes that display biological activities independent of their enzymatic function, including exocytosis induction and insecticidal … WebMar 21, 2024 · GeneCards Summary for PLA2G2A Gene. PLA2G2A (Phospholipase A2 Group IIA) is a Protein Coding gene. Diseases associated with PLA2G2A include Familial …

WebNov 15, 1991 · Phospholipase A 2 (PLA 2) participates in a wide range of cellular processes including inflammation and transmembrane signaling. A human nonpancreatic secretory PLA 2 (hnps-PLA 2) has been identified that is found in high concentrations in the synovial fluid of patients with rheumatoid arthritis and in the plasma of patients with septic shock. WebThe Val279Phe variant of the lipoprotein-associated phospholipase A2 gene is associated with catalytic activities and cardiovascular disease in Korean men. J Clin Endocrinol Metab. 2006;91(9):3521–3527. 54. Xu L, Zhou J, Huang S, et al. An association study between genetic polymorphisms related to lipoprotein-associated phospholipase A2 and ...

WebMar 8, 2024 · The sequences of mammalian phospholipases were collected in the database UniProt by entering the gene names PLA2G1B and PLA2G2A, considering only the ten curated entries for PLA2G1B, and the five curated entries plus five other entries in the case of PLA2G2A. ... The phospholipase A2 superfamily and its group numbering system. …

WebMay 12, 2024 · Ma, Z., Wang, X., Nowatzke, W., Ramanadham, S., Turk, J. Human pancreatic islets express mRNA species encoding two distinct catalytically active isoforms of group … crypto roastWebThis gene is a member of the secretory phospholipase A2 family. It is located in a tightly-linked cluster of secretory phospholipase A2 genes on chromosome 1. The encoded enzyme catalyzes the hydrolysis of membrane phospholipids to generate lysophospholipids and free fatty acids including arachidonic acid. crypto robot investorWeb"Mouse group X secretory phospholipase A2 induces a potent release of arachidonic acid from spleen cells and acts as a ligand for the phospholipase A2 receptor". Arch. Biochem. Biophys. 381 (1): 31–42. doi: 10.1006/abbi.2000.1977. PMID 11019817. Degousee N, Ghomashchi F, Stefanski E, et al. (2002). crypto risk systemWebMar 13, 2024 · In this study, the function of the patatin-like phospholipase gene in V. dahliae (VdPLP, VDAG_00942) is characterized by generating gene knockout and complementary mutants. ... Percudani, R.; Bonfante, P.; Ottonello, S. A nutrient-regulated, dual localization phospholipase A2 in the symbiotic fungus Tuber borchii. EMBO J. 2001, 20, 5079–5090 ... crypto robot scamWebFeb 17, 2024 · The phospholipase A2 (PLA2) gene encodes the enzyme that catalyzes the hydrolysis of phospholipids (PLs) from the sn-2 position. However, little is known about its role in humoral immune responses. crypto robot githubWebCalf skeletal muscle gene expression of patients with PAD and healthy subjects was analyzed using microarrays. The top-ranking gene differentially expressed between PAD and controls (FDR < 0.001) was PLA2G16 , which encodes adipose-specific phospholipase A2 (AdPLA) and is implicated in the maintenance of insulin sensitivity and regulation of ... crypto robot trixWebCytosolic phospholipase A2 is an enzyme that in humans is encoded by the PLA2G4A gene. [5] [6] Function [ edit] This gene encodes a member of the cytosolic phospholipase A2 … crypto robotics